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Prozac: Prozac, trade name of fluoxetine hydrochloride, first of the class of antidepressant medications called selective serotonin reuptake inhibitors (SSRIs). It was introduced by Eli Lilly pharmaceutical company as a treatment for clinical depression in 1986.

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PROZAC and other antidepressant medicines may increase This Medication Guide has been approved by the U.S. Food and Drug Administration.

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